McCoy's 5A (modified) is a universal medium that supports many types of primary cells, established cells lines as well as the proliferation of explants from biopsied tissue. This medium supports the growth of primary mammalian cells derived from normal bone marrow, skin, spleen, kidney, lung, rat embryo, and other tissues.
Provided Complete formulation.

Dr.Thomas McCoy originally formulated McCoy's 5A medium as a modified version of Basal Medium 5A. Unlike other media, McCoy's 5A contains the reducing agent glutathione, bacterial peptone, and high concentrations of glucose. This product also includes Dr. Hsu Hanks' salt additive to support use outside of a CO₂ incubator.

cGMP Manufacturing and Quality Systems
Gibco™ McCoy's 5A (Modified) is manufactured in a cGMP compliant facility in Grand Island, New York. The factory is an FDA-registered medical device manufacturer and is certified to the ISO 13485 standard. To ensure supply chain stability, we also offer the same Gibco™ McCoy's 5A (modified) product (22300-021) manufactured in our Scottish factory. The facility is an FDA-registered medical device manufacturer and is certified to the ISO 13485 standard.

Gibco™ McCoy's 5A (modified) requires serum supplement, usually 10% added Fetal Bovine Serum (FBS). Gibco™ McCoy's 5A (modified) uses a sodium bicarbonate buffer system (2.2 g/L) and therefore requires a 5–10% CO₂ environment to maintain physiological pH.