CRC is used with the Thermo Scientific™ Dionex™ AAA-Direct™ Amino Acid Analysis System for applications where carbohydrates are present but only amino acids are the target species. The CRCs are connected together using the Carbohydrate Removal Accessory (CRA), which consists of a syringe pump and a six-way valve. After carbohydrate removal by CRC, the AAA-Direct system using a Dionex™ AminoPac™ PA10 column switched to an in-line cartridge to separate amino acids without derivatization.