GlycanPac AXH-1 LC columns utilize innovative mixed-mode surface chemistry and weak anion exchange (WAX) and hydrophilic interaction chromatography (HILIC) retention mechanisms to achieve excellent selectivity and resolution. The WAX function provides retention and selectivity for negatively charged glycans, while the HILIC mode separates equally charged glycans based on their polarity and molecular size. As a result, GlycanPac AXH-1 LC columns provide superior glycan separation capabilities.

Unique glycan selectivity based on charge, molecular size and polarity

• Excellent resolution of both native and labeled glycans rate
• Is important for both high-resolution glycan map characterization and simple charge-based glycan quantification analysis
• Compatible with fluorescence and MS detection methods
• High Chromatographic efficiency and excellent column stability

GlycanPac AXH-1 LC columns are based on high purity and spherical silica materials and are available in 1.9 and 3 µm specifications, suitable for UHPLC and Standard HPLC applications. GlycanPac AXH-1 LC columns are available in different sizes to meet the varying resolution, throughput, and instrumentation requirements of your application.