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DNAPac RP columns are constructed of spherical wide pore size 4 µm polymeric resin. The phase is extremely stable and tolerates extreme pH (0-14) and temperature (5-110°C) conditions, and can be operated with mobile phases compatible with direct mass spectrometry. The column is available on both HPLC and UHPLC instruments, enabling high resolution and high throughput for oligonucleotides, and resolving both small and very large dsDNA fragments. DNAPac RP reversed-phase (RP) columns are designed for the separation of oligonucleotides and DNA/RNA fragments. The stationary phase is fully compatible with organic solvents and ion-pairing reagents suitable for mass spectrometry, such as triethylamine (TEA) and hexylamine (HA). The large pore size of the polymeric resin enables efficient separation of larger nucleic acids with low rates of residual contamination.
Column designed for reversed-phase oligonucleotide LC and LC/MS separations- Designed for ion pair reaction of oligonucleotides and double-stranded nucleic acids Phase (IP-RP) separation
- High resolution and high throughput
- Excellent MS compatibility
- Wide operating pH range (0-14) And high thermal stability (up to 110°C)
