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The Animal-Free Human Dendritic Cell Cytokine Package contains the key components required for the culturing of human dendritic cells.< br>
The package contains the following two vials:
• 100 μg Animal-Free Human IL-4 (Cat. No. AF-200-04-100UG)
• 100 μg Animal-Free Human GM-CSF (Cat. No. AF-300-03-100UG)
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. Produced by mast cells , T cells, and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells.
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells.