An improved formula for denaturing RNA samples in any glyoxal gel protocol. The solution to sample volume ratio is lower than in published protocols, so sample precipitation is usually not required before gel loading. Premix ethidium bromide with the solution. 6 tubes, 1 mL each. All Ambion® gel loading solutions are rigorously tested for non-specific endonuclease activity, exonuclease activity, RNase activity and functionality. These solutions are the same ones we use in-house and in our kits.