Dynabeads™ biotin binding agents are 2.8µ m superparamagnetic microspheres that can bind biotinylated antibodies (or other biological ligands) for the isolation of cells of any species such as human, mouse, rat, non-human primates and cell lines.

• Works with any sample and any cell type of any species
• Use biotinylated primary antibodies to quickly and efficiently deplete or positively isolate any target cells for molecular downstream analysis
• Use a mixture of biotinylated antibodies to obtain pure, uncontaminated cells to remove unwanted cells

Suitable for various isolation strategies
Biotinylated primary antibodies can be added into cell samples (indirect technology) or pre-coated on Dynabeads™ Biotin Binding Reagent (direct technology). Regardless of the technology used, when the cell sample is mixed with Dynabeads™ Biotin Binding Reagent, the beads bind the target molecule. Place the sample on the magnetic rack Bead-bound target molecules are separated from the rest of the sample. One or more biotinylated antibodies can be used to remove unwanted cells from a sample (negative isolation), or to capture specific cells for use in downstream experiments (positive isolation). To isolate cells without beads (e.g., flow cytometry), we recommend using biotinylated antibodies plus CELLection™ Biotin Binder KitComposition.

Available for a variety of sample types
Using Dynabeads™ biotin binders you can isolate essentially any species and any starting sample (e.g. whole blood, cord blood, cells in peripheral blood mononuclear cells (PBMC), buffy coat, mouse spleen/lymph nodes, and tissue digest products).

Learn more about Dynabeads™ products
• Get Dynabeads™ products.
• Get the Magnetic StandPerform Dynabeads™ separation.