DynaGreen Protein A/G magnetic beads enable high-performance direct and indirect immunoprecipitation while being environmentally sustainable choose. DynaGreen Protein A/G Magnetic Beads are microplastic-free, sub-micron magnetic beads. Magnetic beads provide reproducible isolation of target proteins in a simple and efficient workflow that can support manual protocols or be automated on KingFisher instruments.

Features include:
• Produces reproducibly high yields and high-quality immunoprecipitation
• Reduces the environmental impact of research
• Improves purity and reduces non-specific binding
• Easily expand and automate operations
• Porous magnetic beads reduce antibody usage

Manual separation is simple, gentle and efficient
DynaGreen Protein A/G magnetic beads are Microplastic-free superparamagnetic beads with surface covalently coupled recombinant Protein A/G. The smaller size of submicron magnetic beads (approximately 250 nm) reduces the sedimentation rate and increases the target capture surface area. Therefore, efficient and high-yield separation of target proteins can be achieved within 80 minutes in a simple direct or indirect immunoprecipitation (bind-incubate-elute) protocol without pre-wash steps.

The magnetic separation technology used by DynaGreen Protein A/G magnetic beads is fast and gentle, producing very little physical pressure on the target protein. Additionally, the non-porous nature of the magnetic bead surface means there is a lower risk of antibodies becoming stuck and becoming inaccessible, minimizing the amount of antibody required to produce accurate and reproducible results. The isolated high-yield and high-purity target proteins are highly compatible with downstream immunoblotting or mass spectrometry.

The following product manual includes a list of required reagents and materials as well as details on compatible buffer formulations.

Fast and reproducible automated workflows
As experimental scale increases to mid- to high-throughput, workflows for DynaGreen Protein A/G magnetic beads can be made seamless using the KingFisher automation platform Seam expansion. The automated protocol takes only 40 minutes to run and processes up to 96 samples per run, significantly reducing hands-on time while maintaining the same reproducibly high target yield and low non-specific binding as the manual protocol.

A certified choice for environmentally sustainable research
Microplastic-free DynaGreen Protein A/G magnetic beads are designed to improve the performance of immunoprecipitation workflows and Environmental factors were taken into consideration. Microplastic-free DynaGreen Protein A/G magnetic beads have been proven to deliver high purity and yield of target proteins in both direct and indirect immunoprecipitation workflows compared to other magnetic bead alternatives. At the same time, the product contains a large number of sustainable product design elements certified by the third-party ACT label by combining the principles of green chemistry and green engineering. Choosing DynaGreen Protein A/G magnetic beads can help reduce the environmental impact of your research without compromising your results.