Mass spectrometry is critical for studying biological compounds. However, many buffers and reagents used in sample preparation can interfere with mass spectrometry analysis, resulting in poor spectral quality and reduced sensitivity. Pierce Peptide Desalting Spin Columns are designed to remove a wide range of contaminants that interfere with hydrophilic samples with minimal sample loss, allowing for sensitive and comprehensive analysis of digested protein samples by mass spectrometry.

• Removes MS-interfering contaminants — Significantly reduces signal suppression and increases sensitivity of mass spectrometry
• High binding capacity — Based on hydrophobic polymers The resin recovers loading amounts of 5 µg to 5 mg of native and TMT-tagged peptides
• Easy to use — The resin is supplied in disposable spin columns that fit into common 2 mL tubes< br> • Compatible — The resin has been validated using a variety of complex samples, including TMT-tagged peptides, and has been shown to be stable under extreme pH conditions