Lycopersicon esculentum (Tomato) Lectin (LEL, TL), DyLight 488, is a bright-green LEL- fluorophore conjugate. The tomato lectin LEL is widely used as marker of blood vessels and microglial cells in rodents and in neuroscience research. It is a valuable tool in studies of rodent tumor angiogenesis and the tracing of neovascular development in xenograft models and brain research. LEL-DyLight 488 can be applied directly to tissue sections, or it can be introduced through intravascular perfusion for fluorescence detection.
View complete list of fluorescent dye-conjugated lectins ›• Very bright DyLight 488 conjugate detected with traditional FITC filter set, Ex/ Em: 493/518 nm
• Applications: immunofluorescence, glycobiology
• Sugar specificity: [GlcNAc] 1,3-N-acetylglucosamine
• Inhibiting/eluting sugar: chitin hydrolysate
• Blood group specificity : non-specific
• Unconjugated lectin molecular weight: 71 KDa.
• Immunofluorescence working concentration: 5–20 μg/mL
LEL is a very stable single-subunit glycoprotein containing ∼50 percent arabinose and galactose and may form multimeric aggregates in solution. It is provided at a 1 mg/mL concentration in 10 mM HEPES, 0.15 M NaCl, pH 7.5, 0.08% sodium azide, 0.1 mM Ca
2+. If a precipitate forms upon long-term storage, warm to 37°C.
For Research Use Only. Not for use in diagnostic procedures.< /div>