Thermo Fisher 60109-110 Each SMART DigestPepsin kit (including collection plate)
$1358.33 / Parcel$1489.39 Min.order:1
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Get high-quality results using the Thermo Scientific™ SMART Digest™ Pepsin Kit in your peptide mapping and peptide quantification workflows. This kit is a major advance in sample preparation for biopharmaceutical protein research, providing fast and easy protein digestion with high reproducibility, sensitivity and data quality in a format compatible with automation. The SMART Digest Pepsin Kit is an important improvement over today's lytic protein digestion technologies that are unreproducible, less sensitive, and have long relied on methods that cannot be automated.

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How SMART Digest Pepsin Kit Works
Pepsin preferentially cleaves proteins at the carboxyl group of aromatic amino acids such as phenylalanine, tryptophan, and tyrosine. It does not cleave at bonds containing valine, alanine, or glycine. Pepsin is commonly used to generate antibody fragments. Pepsin generates F(ab')2 fragments by removing only the portion of the Fc domain beyond the hinge region. The resulting F(ab')2 fragment consists of two antibody-binding Fab' fragments linked to disulfides in the hinge region.