Molecular Probes™ fibrinogen conjugates are prepared by attaching fluorescent dye molecules to purified human fibrinogen (each Fibrinogen molecules are linked to approximately 15 dye molecules), and the conjugate is purified to remove unreacted dye and then lyophilized for storage.

Fluorescently labeled fibrinogen has proven to be a valuable tool for studying platelet activation and subsequent fibrinogen binding. For example, fluorescein-labeled fibrinogen has been used to detect fibrinogen bound to activated platelets by flow cytometric analysis.

Human Fibrinogen Conjugate Specifications:
• Label (excitation/emission wavelength): Alexa Fluor™ 647 (approximately 650/668 nm)
• Spectrum with Cy™5 Dye conjugates are similar
• Lyophilized products are used after dissolving in a buffer (such as sodium bicarbonate at pH 8.3)
• Fluorescence is typically detected using fluorescence microscopy or flow cytometric analysis< br>
Find more probes for cell adhesion and receptor binding
See Probes for cell adhesion, chemotaxis, multidrug resistance, and glutathione—Section 15.6 and Probes for tracking receptor binding and phagocytosis—Section 16.1 for more information about these probes.

Research use only. Not for therapeutic or diagnostic use in humans or animals.